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¡¡¡¡Õª    Òª£º¡¡¼×¿ÇËØ¿Éת»¯Îª¶àÖָ߸½¼ÓÖµ²úÆ·ºÍϵÁл¯Ñ§Æ·¡£¸ÃÎÄ×ÛÊöÁËÒԼ׿ÇËؼ°Æä½µ½â²úÎïN-ÒÒõ£°±»ùÆÏÌÑÌÇת»¯ÖƱ¸Æ½Ì¨»¯ºÏÎï3-ÒÒõ£°±»ù-5-ÒÒõ£»ù߻ૺÍÆäËûº¬µª»¯ºÏÎïµÈ»¯Ñ§Æ·µÄ×îÐÂÑо¿½øÕ¹¡£¶ÔÒÔ3-ÒÒõ£°±»ù-5-ÒÒõ£»ùß»à«×÷Ϊƽ̨»¯ºÏÎï½øÒ»²½×ª»¯ÎªÆäËû»¯ºÏÎï½øÐÐÁ˸ÅÊö£¬²¢¶ÔÕâЩÁìÓòµÄÑо¿·½Ïò½øÐÐÁËÕ¹Íû£¬ÒÔÆÚ´Ù½ø¼×¿ÇËØת»¯º¬µª»¯Ñ§Æ·ÁìÓòµÄ·¢Õ¹¡£

¡¡¡¡¹Ø¼ü´Ê£º¡¡¼×¿ÇËØ; 3-ÒÒõ£°±»ù-5-ÒÒõ£»ùß»à«; N-ÒÒõ£°±»ùÆÏÌÑÌÇ; º¬µª»¯Ñ§Æ·;

¡¡¡¡Abstract£º¡¡Chitin can be converted into a variety of high value-added products and chemicals. The latest research progress in the conversion of chitin and its degradation product of N-acetyl glucosamine to nitrogen-containing chemicals such as 3-acetamido-5-acetylfuran and other N-containing compounds is reviewed. The further conversion of 3-acetamido-5-acetylfuran as a platform compound to other compounds is also summarizes. The research directions in these fields are prospected so as to promote the development of chitin conversion into nitrogen-containing chemicals.

¡¡¡¡Keyword£º¡¡chitin; 3-acetamido-5-acetylfuran; N-acetyl-D-glucosamine; nitrogen-containingchemicals;

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ͼ1  ¼×¿ÇËØ¿ÉÖƱ¸µÄ»¯Ñ§Æ·[26]

¡¡¡¡Fig. 1  Chemicalsprepared from chitin[26]

¡¡¡¡ÕâЩ»¯ºÏÎï¿É·ÖΪÁ½À࣬һÀàÊDz»º¬µªµÄ»¯ºÏÎ3~7£©£¬Ö÷ÒªÓÐÒÒËᣨ4£©¡¢¼×Ëᣨ5£©¡¢ÒÒõ£±ûËᣨ6£©¡¢×óÐýÆÏÌÑÌÇͪ£¨7£©ÒÔ¼°5-ôǼ׻ù¿·È©£¨3£©[27]µÈ£¬ÕâЩ»¯ºÏÎï¿ÉÒÔ´ÓÆäËû²»º¬µªµÄ¶àÌÇ/µ¥ÌÇÖƱ¸µÃµ½¡£ÁíÒ»ÀàÊǺ¬µªµÄ»¯ºÏÎ8~16£©£¬Ö÷Òª°üÀ¨3A5AF£¨9£©¡¢N-ÒÒõ£»ùµ¥ÒÒ´¼°·£¨10£©¡¢ßÁण¨11£©¡¢ßÁ¿©£¨12£©¡¢ßÁຣ¨13£©¡¢ôÇÒÒ»ù-2-°±»ù-2-ÍÑÑõ¼ºßÁà«ÌÇÜÕ£¨15£©¡¢µ¥ÒÒ´¼°·£¨16£©µÈ¡£GlcNAc£¨14£©ÊÇÒ»ÖÖ°±»ùÌÇ£¬ÊǼ׿ÇËؽµ½âµÃµ½µÄµ¥ÌÇ[16]¡£Ïà¶ÔÓڼ׿ÇËؽÏÄÑÆÆ»µµÄ½á¹¹£¬ÒÔGlcNAcΪԭÁÏÓÐÒ»¶¨µÄÓÅÊÆ£¬°üÀ¨Ò×Èܽ⡢Ŀ±ê²úÎïµÄÊÕÂʽϸߵȡ£GlcNAc¿ÉÖƱ¸¸÷Öָ߸½¼ÓÖµµÄº¬µª»¯ºÏÎͼ2£©£¬Èç3A5AF£¨9£©¡¢É«Ô­Ìå¢ñ¡¢¢ó£¨17¡¢18£©¡¢2-ÒÒõ£°±»ù-3,6-ÍÑË®-2-ÍÑÑõ-D-ÆÏÌÑÌÇß»à«ÌÇ£¨19£©¡¢2-ÒÒõ£°±»ù-3,6-ÍÑË®-2-ÍÑÑõ-D-¸Ê¶߻à«ÌÇ£¨20£©µÈ£¬ÕâЩ»¯ºÏÎïÓнϺõÄÉúÎï»îÐÔ£¬¿É×÷Ϊ¹¦ÄÜÐÔµÄʳƷÌí¼Ó¼Á[28]£¬»¹¿ÉÖƱ¸ÓÃ×÷ÖÎÁÆ×ÔÉíÃâÒßÐÔ¼²²¡¡¢²¡¶¾¸ÐȾºÍ¼ÄÉú³æ¸ÐȾµÄÒ©Îï[29]¡£

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¡¡¡¡Fig.2  DifferentN-containing compounds prepared GlcNAc

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¡¡¡¡Fig.3Possiblereaction process of conversionof GlcNAc to 3A5AF[35]

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¡¡¡¡Fig. 4Possiblereaction process of conversion of chitin to 3A5AF[26]

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¡¡¡¡Fig.5N-containing compounds synthesized by 3A5AF

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¡¡¡¡Fig.6Different N-containing compounds prepared from chitin

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